Hypermethylated APC in serous carcinoma based on a meta-analysis of ovarian cancer

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Hypermethylated APC in serous carcinoma based on a meta-analysis of ovarian cancer

BACKGROUND The reduced expression of the Adenomatous polyposis coli (APC) gene, a tumor suppressor gene, through promoter hypermethylation has been reported to play a key role in the carcinogenesis. However, the correlation between APC promoter hypermethylation and ovarian cancer (OC) remains to be clarified. METHODS A comprehensive literature search was carried out in related research databa...

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ژورنال

عنوان ژورنال: Journal of Ovarian Research

سال: 2016

ISSN: 1757-2215

DOI: 10.1186/s13048-016-0271-6